TLDR: So this is saying there are some genetic variants that cause cascading protein malformations in developing brains, which leads to a higher risk of developing certain psychiatric disorders, including autism, ADHD, schizophrenia, bipolar disorder, major depressive disorder, Tourette syndrome, obsessive-compulsive disorder, and anorexia.
It doesn’t sound super surprising that different malformations in the brain even though caused by the same underlying condition can result in very varied effects on behavior.
Good stuff though. (The research)
I don’t know if a pleiotropic relationship between 109 different genes can be called “the same root cause”. Maybe “a large complex of interacting causes”?
Fair point!
Interesting article. Thanks for this post!
