r/IAmA Aug 11 '21 Bravo Grande! 1 Take My Power 1 Silver 11 Gold 2 Helpful 16 Wholesome 3 Hugz 12

I am a cannabis scientist, ask me anything THC, CBD, or any other cannabis related questions, AMA Science

Hi Reddit, Gair Laucius, Chief Science Officer from High Purity Natural Products here, I am here to answer your questions about cannabis, CBD, THC, or any other cannabinoids you want to ask about.

This AMA is closed! Thanks everyone for the great questions, I'm sorry I couldn't answer them all - If you'd like to know more about my company, please visit https://highpuritynaturalproducts.com/about-us/

My experience:

I am an experienced cannabis researcher with expertise in ethanol and super-critical CO2 extraction, gas chromatography mass spectrometry, and high performance liquid chromatography analytics.

I have also conducted research on Cannabis sativa with specific focus on proteins related to cannabinoid biosynthesis pathways. Extensive research experience with DNA and RNA extraction with downstream PCR and qPCR. Highly experienced in terpene and cannabinoid extraction and profiling using HPLC and GCMS.

If it has anything to do with weed, AMA!

Proof: https://twitter.com/HighPurityNP/status/1425475523858341889

Edit: 12:15PM Will be taking a short break for lunch, will return for some more questions shortly. Keep them coming!

Edit2: 1:00PM Wrapping up for now, hope to answer a few more questions later this evening. Thank you to all who asked questions!

11.4k Upvotes

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u/Master_Paladin Aug 11 '21

Is Delta 8 safe?

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u/HPNP Aug 11 '21 edited Aug 11 '21 Gold Hugz

As an isolated cannabinoid, Delta-8 THC is lacking in peer reviewed research but has been shown to have a similar effect to delta-9 THC both being psychoactive (Delta-8 less psychoactive than delta-9). Delta-8 THC presents concern for me not because of the cannabinoid but because of the manufacturing process behind making it. Delta-8 is converted from CBD by using harsh chemicals and solvents and if care is not taken to remove these byproducts there is the potential for harm. As a consumer it is extremely difficult, almost impossible to verify how well a delta-8 product was manufactured. My recommendation is to not use delta-8 until more regulation can ensure safety across the board.

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u/RooXOXXO Aug 11 '21

Very interesting response. Thank you.

Could the same be said for other d9 concentrates on the black market? Would you say that delta 8 is safer than those?

It seems these products are used mostly in grey states and states where medical/recreational hasn’t taken off yet.

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u/HPNP Aug 11 '21

Sourcing anything that is unregulated such as black market THC is dubious at best. The benefit of purchasing products from legal recreational or medicinal dispensaries is that these programs have regulations to ensure that the products that are sold are tested to ensure safety. Products are tested for Heavy metals, residual solvents, microbials, molds and mycotoxins, and cannabinoids at minimum. The same information cannot be provided for unregulated markets

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u/spineofgod9 Aug 11 '21

Too bad my dirt poor ancestors had to land in texas and leave me stuck here all these years later. So, black market it is. Unless hell freezes over, anyway.

Y'know, they didn't even have the decency to get rich and move to new england. Jerks.

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u/lukamic Aug 12 '21

I thought hell froze over ealier this year

2

u/spineofgod9 Aug 12 '21

It thawed again. Then got hotter than ever.

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u/lukamic Aug 12 '21

My condolences

3

u/potato_aim87 Aug 11 '21

Thanks for doing this AMA. I can't substantiate this but I have heard rumors that some of the labs that do the testing for some states can be bought or that their results are falsified. Do you any knowledge on that? What would your advice to consumers be about the legitimacy of lab results?

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u/deekaydubya Aug 11 '21

Important to note D8 is not a black market, although there seem to be almost as many counterfeit carts as the D9 market

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u/drunkdog Aug 11 '21

If you buy from reputable sources you get a coa. Now what the impurities are is another story

3

u/perfecto_falcon Aug 11 '21

not true at all. plenty of "black"/"gray" market products get tested, and some even more rigorously. definitely more topically.

plenty of loopholes in the "legal" market to sluff off products that don't pass testing.

e.g. Companies using the same test for up to two years, fudging allowable limits, bait-and-switch, sample swapping etc etc

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u/notoriousCBD Aug 11 '21

This absolutely is true. Every batch harvested is required to go through the battery of tests relative to black market flower, which of course has no requirements. He never said black market isn't tested, just that it doesn't have the requirements.

Of course there are loopholes, and some are pretty ridiculous. For Colorado, each batch much have a certain percentage of the final mass go through all of these tests. It is very easy to pick a sample that isn't representative of the whole batch and get the numbers you're looking for. But this would also be easy for any black market grower to do as well. It's why I don't necessarily trust terpene or cannabinoid percentages I see labeled, unless I do it myself or I trust the tester.

I've never purchased black market Cannabis that has been tested with HPLC or shown a Total yeast and mold dilution summary.

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u/perfecto_falcon Aug 11 '21

lol you guys are cute. Defensive much?

I'd bet money you've purchased "black market" Cannabis fully tested straight out of a dispensary.

You contradict yourself multiple times and claim to disagree with me while agreeing with me at the same time. "He never said black market isn't tested", oh he just implies it? "Every batch must be tested" but "of course there are loopholes" lol great logic. What relevance does "But this would also be easy for any black market grower to do as well" have here if there aren't any regulations? You're defending the process but at the same time "don't necessarily trust terpene or cannabinoid percentages I see labeled, unless I do it myself or I trust the tester."

Plenty of dispensaries sell straight trash buds, clones with pests, mold, pre-rolls that have been blasted, yadda yadda.

The exceptions to the lists and increases of "acceptable levels" have all been upped too.

On and on...

TL;DR I get, it you like marketing pretending to be science. And you mostly agree with me, but also don't and like contradicting yourself and making confusing semi-related assertions based on unclear premises. Cool.

2

u/notoriousCBD Aug 12 '21

Yes, I defended that guy's statements, because they are all true. Just like you disagreed with what I typed and defended yourself, that's how this works in typical discourse. Being defensive if that's what you want to call it.

I should've been more specific in saying that by black market I meant grown on the black market not just sold. I figured that you would get that in context of the larger conversation. If you are including that legally grown, but illegally sold, then all of that flower was required to have been tested as well. But even stuff sold on the black market could be anything, even if it's packaged as something purchased from the dispensary.

I disagreed with you commenting that the other guy was wrong and agreed with you that there are loopholes, two different premises. You can logically disagree with one premise and agree with another. His comment, word for word, said that "The same information cannot be provided for unregulated markets," in regards to testing standards, which is completely true. You can believe that he implied more, but I do not get that implication there.

Legally being required to test every batch and saying there are loopholes are both correct statements, wheres the flaw in that logic? Those things are not mutually inclusive. The state of Colorado legally requires the dispensary I work for, as a scientist, to test every batch for total yeast and mold, cannabinoids, terpenes, active water, heavy metals and, sometimes, mycotoxins. And, there are definitely loopholes that allow the dispensary to throw off a test, or show results that aren't representative of the whole batch. There is no way we could possibly not test a batch, though. I'm directly involved with all of our testing so I know every loophole to use. This is why I don't trust cannabinoid numbers at the dispensary, and I really don't even care when I purchase. I'm looking at the flower not the numbers when I buy for myself.

You say I'm defending the process, but I don't know what process I'm defending. I can say that the process (lab required testing) is real, and legally required, but I don't agree with some of the standards that have been set. That's why I'm on the ASTM board to help set those standards. In Colorado, none of the "acceptable levels" have changed since I've been working in the industry, and most of those follow any food industries standards.

Yes, tons of dispensaries sell clones that are covered in a variety of pests, as well as very low quality flower and a bunch of other shit that should never touch consumers hands. The illegally grown black market is also full of that as well.

TL;DR You can argue semantics all you want, but the logic is solid. People CAN agree with one thing and disagree with another, that's not contradiction. It's a crazy thought, I know, but you'll catch on. And, your mom called me cute the other night too :)

1

u/Faxme123 Aug 12 '21

Have you tested d8?

1

u/notoriousCBD Aug 12 '21

No, the dispensary I work for is not involved with it whatsoever.

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u/3eb489 Aug 11 '21

Yeah this dude is an obvious corporate mouthpiece here to promote the company he works for. You can get higher quality cannabis on the so called “black market” in legal states at a much better price

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u/ExpiredAmmo Aug 11 '21

The unregulated stuff in British Columbia is by far better and cleaner than the legally grown garbage.

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u/Violaceum Aug 11 '21

You might want to look at the report published by the BC government about 2 months ago that says otherwise. They examined microbes and pesticides from black market cannabis and every one of them failed the standards that Health Canada makes the LPs follow. Some of them were 40x over the allowable limits for pesticides.

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u/ExpiredAmmo Aug 11 '21

As usual, the government findings are questionable. Where did they get it from.

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u/Violaceum Aug 11 '21

Lol whoops, I guess I'm wasting my time here with facts then.

-8

u/ExpiredAmmo Aug 11 '21

So the guberment confiscates some weed from a dodgy store, tests it and that is supposedly representative of all weed everywhere. Gotcha.

I have GC test results. You haven't presented facts, just an anecdotal claim. Don't hurt your arm patting yourself on the back bro.

3

u/3eb489 Aug 11 '21

It’s the same in California. While there is high quality legal cannabis, it’s incredibly overpriced at the dispensaries. And at the same dispensaries you’ll find tons of low quality cannabis. It’s better to get your weed from a farmer or a plug who’s directly connected to a farm.

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u/ExpiredAmmo Aug 11 '21

I find most stores have 2 or 3 good things and 65 jars of meh.

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u/notoriousCBD Aug 11 '21

How do you know that your unregulated flower is "cleaner?"

1

u/ExpiredAmmo Aug 11 '21

gas chromatography

2

u/notoriousCBD Aug 11 '21

What are you testing for, using GC-MS, that would make your plants not clean?

0

u/ExpiredAmmo Aug 12 '21

unwanted peaks

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u/notoriousCBD Aug 12 '21

Just because I need more of this....What are the names of the specific compounds you are using GC-MS to identify, that will also make your plants not clean?

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u/Dudefest2bit Aug 11 '21

Are delta 8 carts supposed to be clear?