MMOs are probably a good indication.
I think researchers (or just casual investigators) studied MMOs to see how people might react in a plague situation (I want to say WoW, but it might’ve been EverQuest).
They ended up discarding/writing off their findings because they figures that there wouldn’t ACTUALLY be trolls who’d go around spreading the virus on purpose, and also that because the virus only had negative effects, no one would be doing actions that would nearly guarantee infection.
Of course, 2020 showed us that we really should’ve been looking at what people do in MMOs…
Yeah it was WoW early on, a debuff from a boss was bugged and was allowed to spread outside the raid.
And they also had the turn-into-a-zombie plague event when Wrath launched, too.
As I recall, that mostly just made everyone rage because the assholes running around spreading it everywhere were just annoying the crap out of everyone and the general thought is they just needed to fuck off and find something else to do.
Or, basically, Covid.