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Red Hat (RHEL) is not based on any other distro, like Ubuntu is with Debian. RHEL is downstream of Fedora, meaning that RHEL developers can work on code that affects Fedora AND RHEL. This is not really true of Debian and Ubuntu. They are distinct projects with different goals. In many ways, Ubuntu is beholden to what Debian does. This isn’t usually a problem because Debian is very conservative in its approach to software. Ubuntu doesn’t usually have to worry about Debian screwing with something Ubuntu is trying to do.
Which, is all to say that there is no other distribution you can officially equate to RHEL like you can with Debian & Ubuntu.
I imagine this would be up to the application. What you’re describing would been seen by the OS as the device becoming unavailable. That won’t really affect the OS. But, it could cause problems with the drivers and/or applications that are expecting the device to be available. The effect could range from “hm, the GPU isn’t responding, oh well” to a kernel panic.