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Joined 11 months ago
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Cake day: August 2nd, 2023

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  • Pipoca@lemmy.worldtoFunny@sh.itjust.worksExpert swordsmen
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    4 months ago

    The only problem is that the functional replica anime sword section is probably going to be entirely empty. They’re basically all decorative wall hangers.

    They’ll differ in build quality, though. Some might break if you swing them hard, others might break if you hit something with them.






  • Pipoca@lemmy.worldtoFunny@sh.itjust.worksExpert swordsmen
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    4 months ago

    it’s not unreasonable to expect the cool prop to feel like it’s not trying to fly across the yard if you swing it around.

    You might think that, but most of these are called wall hangers for a reason.

    Many of them have rat-tail tangs or are made with stainless steel. They might feel balanced, but are liable to snap if you swing them around.





  • Pipoca@lemmy.worldtoCool Guides@lemmy.caThe lethal doses of 55 substances
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    4 months ago

    More than 1200 mg of pure THC, or 1200mg of cannabis leaves?

    Those aren’t even remotely the same thing, in the same way that 12oz of beer and 12oz of everclear are very different, or 1g of pure nicotine is very different than 1g of tobacco leaves.

    Not to mention, LD50 is about a single dose. There’s a big difference between taking one shot an hour for 16 hours straight, and chugging 16 shots in one go.


  • 16.5 mg is 16500 μg. So a 70kg person would need over 1 million μg.

    According to https://www.trippingly.net/lsd/the-lsd-dosage-guide, 25 μg is where visual effects start.

    700 to 1000 μg. Full out-of-body experiences. Synesthesia more likely. Religious imagery often strong. Entire loss of rationality, lack of ability to walk or interact in any meaningful way.

    1500 μgs+ Experiences may be similar to DMT but extended. Basic body functions are challenging. Vision is consumed by hallucinations. No sense of self remains. Audio hallucinations may be strong. Standard reality no longer applies. Merging with objects likely. No type of rational thought left.

    A deadly dose is around 800x higher than that. You wouldn’t be as high as a kite. You’d be as high as Voyager one.


  • Also: notice the LD50 for vitamin D is 37mg/kg.

    Based on https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709011/, a therapeutic regime for very low vitamin D levels is taking 6k IU per day for 3 months, or 50k IU once a week for 2 months.

    1 IU is 0.025 μg, or 0.000025 mg. 50k IU is 1.25 mg.

    I buy bottles of 5k IU vitamin D pills. Each bottle has 90 pills. That’s 11.25 mg of vitamin D per bottle. I’d need to take well over 200 bottles of these pills to have a 50% chance of dying.

    Yes, an objectively small amount of purified vitamin D will kill you. But it’s quite safe in practice because the environment only has objectively tiny amounts of the stuff. Even high dose pills contain a tiny amount of the stuff.


  • Pipoca@lemmy.worldtoCool Guides@lemmy.caThe lethal doses of 55 substances
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    4 months ago

    Keep in mind: a single extra strength Tylenol is 500mg. A standard dose for a headache is 2 pills, or 1000mg.

    Weed gummies come in doses of 1mg to 100mg. 1mg is a microdose people might take for mild pain or stress, while 50+mg is a dose for cancer patients often take. A standard dose for occasional recreational highs is 5mg; they recommend first timers start at 2.5mg.

    LD50 compares things by weight, rather than dose. By weight, THC is slightly more toxic than acetaminophen. But in terms of the number of therapeutic doses it takes to kill you, it’s way, way safer.


  • LD50 is usually determined using rodent studies. How much Vitamin D causes an overdose in half of a population of mice?

    The dose makes the poison.

    And with drug safety, in practice LD50 is less important than how close a therapeutic dose is to a lethal one. If a drug takes 2g/kg to kill you but you need 1g/kg to work, that’s way more dangerous than one that takes .02g/kg to kill you but only needs .0002g/kg to work.



  • Ish.

    There’s precisely zero skill involved in e.g. roulette.

    Poker, fantasy football, and horse betting though, are influenced by skill. But they’re all clearly still gambling.

    The important thing in those 3 is that you’re not betting against the house. You’re betting against other players, and that you’re the smart enough to come out on top even after the house takes their cut. Unless you’re Nate Silver, though, chances are you’re not the smartest person in the room.